Florfenicol Injection

Amide antibiotics. Used for infections caused by Pasteurella and Escherichia coli.

Advantages:
1. Extremely broad antibacterial spectrum: highly effective against Gram-positive bacteria, Gram-negative bacteria and mycoplasma.
2. Fast-acting & long-lasting with high bioavailability.
3. High concentration in the lungs; the first choice for severe respiratory diseases.
4. Advanced technology, low irritation and easy injection.
5. Wide safety margin and flexible application.

Availability:

Quantity:



Inquire Add to Basket

Florfenicol Injection Pharmaceutical Drugs Swine

Product Description

Product Description

Veterinary Prescription Drug

[Veterinary Drug Name]

Generic Name: Florfenicol Injection

[Composition] Florfenicol

[Character] This product is a colorless to slightly yellow clear liquid.

[Pharmacological Action]

Pharmacodynamics Florfenicol is a broad-spectrum antibiotic of the amphenicol class, acting as a bacteriostatic agent. It exerts its effect by binding to the 50S ribosomal subunit and inhibiting bacterial protein synthesis. It demonstrates strong antibacterial activity against a variety of Gram-positive and Gram-negative bacteria. Pasteurella haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae are highly sensitive to florfenicol.The in vitro antibacterial activity of florfenicol against many microorganisms is similar to or stronger than that of thiamphenicol. Some bacteria resistant to amphenicols due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be sensitive to florfenicol. It is mainly used for bacterial diseases in swine, poultry, and fish caused by sensitive bacteria, including respiratory diseases in cattle and swine caused by Pasteurella haemolytica, Pasteurella multocida, and Actinobacillus pleuropneumoniae; typhoid and paratyphoid fever caused by Salmonella; fowl cholera, pullorum disease, and colibacillosis in chickens; as well as bacterial septicemia, enteritis, and red skin disease in fish caused by Pasteurella, Vibrio, Staphylococcus aureus, Aeromonas hydrophila, enteritis bacteria, etc.

Pharmacokinetics Florfenicol is rapidly absorbed after oral administration. Therapeutic concentrations can be detected in the blood approximately 1 hour later, and peak plasma concentrations are reached within 1-3 hours. The bioavailability is over 80%. Florfenicol is widely distributed in animals and can cross the blood-brain barrier. It is mainly excreted in urine in its prototype form, with a small amount eliminated in feces.

[Drug interactions]

(1) Macrolides and lincosamides share the same target site as this product, all binding to the 50S subunit of bacterial ribosomes. Concurrent use may result in mutual antagonism.

(2) It may antagonize the bactericidal activity of penicillins or aminoglycosides, although this has not been demonstrated in vivo in animals.

[Indications]

Amide antibiotics. Used for infections caused by Pasteurella and Escherichia coli.

[Administration and Dosage]

Intramuscular injection. Single dose: 0.067 ml per kg body weight for chickens; 0.05–0.067 ml per kg body weight for pigs. Administer once every 48 hours, for 2 consecutive treatments.

For fish: 0.0017–0.0034 ml per kg body weight, once daily.

[Adverse Reactions]

(1) The product may exert certain immunosuppressive effects when used at doses higher than recommended.

(2) It has embryotoxicity. Use with caution in livestock during pregnancy and lactation.

[Precautions]

(1) Forbidden for use in laying hens during the laying period.

(2) Forbidden for use in animals during vaccination or with severely impaired immune function.

(3) Animals with renal insufficiency should receive an appropriate dose reduction or extended dosing interval.

[Withdrawal Period] Pig 14 days, chicken 28 days, fish 375 days.

[Specification] 100ml : 30g

[Packaging] 100ml/bottle

[Storage] Sealed storage.