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VAvi NI-CM
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As a leading manufacturer and supplier of veterinary biologicals, we provide this highly purified, inactivated avian vaccine designed for large-scale poultry operations. Formulated to combat critical respiratory and systemic threats, this emulsion delivers consistent flock protection.
Directly sourced from the manufacturer, ensuring strict quality control and continuous traceability.
Ideal for volume procurement by large agricultural facilities and centralized farming networks.
Dual-strain formulation targeting key poultry diseases to streamline immunization schedules and reduce labor.
The Newcastle Disease and Infectious Bronchitis Vaccine, Inactivated (Strain Clone 30+Strain M41) presents as a premium, milky-white emulsion, expertly homogenized to ensure a smooth, uniform consistency that flows effortlessly through automated injection equipment. Upon visual inspection, the liquid exhibits a flawless, opaque white hue, indicative of its highly refined adjuvant and superior emulsification process. This precise pharmaceutical formulation is engineered to provide robust, long-lasting immunological defense against two of the most economically devastating viral pathogens in the global poultry industry. By integrating high-titer antigens into a stabilized matrix, the vaccine facilitates a slow, sustained release upon administration, thereby maximizing the immunological cascade while minimizing tissue irritation at the injection site. For agricultural operators managing extensive flocks, implementing this prophylactic solution translates directly into enhanced survivability, optimized feed conversion ratios, and safeguarded egg production metrics. The meticulously crafted emulsion not only ensures exceptional physical stability during cold-chain transport but also guarantees a reliable, stress-free administration experience, ultimately securing the long-term profitability and health baseline of your commercial poultry assets.
| Veterinary Drug Category | Veterinary Non-prescription Drugs |
|---|---|
| Generic Name | Newcastle Disease and Infectious Bronchitis Vaccine, Inactivated (Strain Clone 30+Strain M41) |
| Trade Name | VAvi NI-CM |
| Composition | The vaccine contains inactivated Newcastle disease virus Clone30 strain (virus content before inactivation ≥ 2×108.0 EID50/0.1ml) and infectious bronchitis virus M41 strain (virus content before inactivation ≥ 2×106.0 EID50/0.1ml). |
| Character | Milky - white emulsion. |
| Function and Purpose | It is used for the prevention of Newcastle disease and infectious bronchitis in chickens. The immunity period is 4 months. |
| Administration and Dosage | For subcutaneous or intramuscular injection. Administer 0.3 ml per chicken aged 1 - 4 weeks, and 0.5 ml per chicken over 4 weeks of age. |
| Adverse Reactions | Generally, no visible adverse reactions are observed. |
| Precautions | 1. This product is only used for the immunization of healthy chickens. 2. Bring the vaccine to room temperature before use. Shake it thoroughly before use. The instruments used for vaccination should be clean and sterile. 3. Once the vaccine bottle is opened, use it up within the same day. 4. Routine aseptic procedures should be followed during the vaccination process. 5. Do not freeze the vaccine. Do not use it if it has broken emulsion. 6. The vaccine bottles and unused vaccine should be disinfected. |
| Specification | (1) 100 ml/bottle; (2) 250 ml/bottle; (3) 500 ml/bottle |
| Storage and Shelf Life | Store at 2~8°C. The shelf life is 12 months. |
| Packaging | (1) 100 bottles/carton; (2) 40 bottles/carton; (3) 24 bottles/carton; (4) 20 bottles/carton |
| Manufacturer | Qingdao Vland Animal Health Group Co., Ltd. |
| Usage Restriction | To be used only under veterinary supervision. |
Securing the health of commercial poultry requires a biological tool that balances potency with physiological safety. This inactivated emulsion is engineered to deliver precise immunological stimulation without compromising the daily growth or production metrics of the flock.
Dual-Pathogen Defense: Simultaneously targets Newcastle Disease and Infectious Bronchitis, streamlining vaccination schedules and reducing handling stress on the birds.
Exceptional Homogeneity: The milky-white emulsion maintains a uniform suspension, ensuring every exact dose drawn contains the precise antigen payload required for optimal seroconversion.
Syringe Compatibility: The refined viscosity of the liquid allows for smooth passage through standard veterinary needles, minimizing hand fatigue for operators during mass administration.
Optimized Adjuvant Integration: Utilizes a premium carrier matrix that promotes a slow, sustained absorption rate, drastically lowering the risk of localized site reactions or systemic shock.
Extended Shelf Stability: Formulated to resist degradation when stored properly under cold-chain conditions, maintaining peak viral titer integrity for a full twelve months.
The foundation of any highly effective biological preventative lies in the selection and concentration of its active viral components. This formulation utilizes an industry-recognized, classic combination designed to elicit a profound immune response.
Clone 30 Strain Integration: Features the highly immunogenic Newcastle disease virus Clone 30 strain, providing a targeted defense mechanism against systemic viral replication.
M41 Strain Inclusion: Incorporates the infectious bronchitis virus M41 strain, specifically chosen for its proven efficacy in shielding the delicate respiratory tract of commercial poultry.
Exceptional Viral Titers: Delivers a massive antigen payload, with pre-inactivation virus content strictly maintained at ≥ 2×108.0 EID50/0.1ml for NDV and ≥ 2×106.0 EID50/0.1ml for IBV.
Precision Protection: This high-density antigen profile ensures that even birds with varying maternal antibody levels receive a potent enough stimulus to develop active, lasting immunity.
Advanced manufacturing processes define the physical and biological performance of this emulsion. The meticulous attention to the physical state of the liquid guarantees both safety and efficacy during mass deployment.
Premium Milky-White Emulsion: Visually distinct, the flawless opaque appearance signifies a perfectly balanced matrix, completely free from phase separation.
Advanced Emulsification Craftsmanship: The microscopic droplet size within the emulsion ensures that the viral particles are evenly distributed, preventing dose inconsistency.
Sustained Antigen Release: The high-quality adjuvant acts as a depot at the injection site, releasing the active components gradually to provide continuous, low-level immune system stimulation.
Minimized Inflammatory Response: Engineered to be highly biocompatible, the formulation drastically reduces tissue irritation, swelling, or localized necrosis post-injection.
Zero Visible Adverse Reactions: Extensive field application demonstrates that flocks tolerate the administration exceptionally well, maintaining normal feeding and drinking behaviors immediately following the procedure.
The economic viability of large-scale poultry operations hinges on minimizing mortality and maximizing production output. This vaccine is calibrated to provide an extended window of biological security.
Four-Month Protection Window: A single, properly administered dose establishes a robust immunological shield that actively circulates for a full 120 days.
Broiler Cycle Coverage: The extended immunity period perfectly encompasses the entire lifespan of standard commercial meat birds, eliminating the need for mid-cycle booster interventions.
Layer and Breeder Preparation: Provides a critical, high-titer antibody foundation for birds entering their peak reproductive phases, safeguarding against sudden drops in egg production.
Mortality Reduction: By effectively neutralizing field challenges from NDV and IBV, the vaccine significantly lowers overall flock culling rates and unexpected die-offs.
Economic Safeguard: The reliable efficacy directly translates to improved feed conversion and higher final processing yields, protecting the facility's bottom line.
Efficiency on the farm requires clear, standardized procedures. This product is accompanied by precise operational guidelines that align perfectly with the fast-paced environment of commercial agricultural facilities.
Age-Specific Dosing: Provides distinct volumetric guidelines, requiring exactly 0.3 ml for younger birds (1-4 weeks) and 0.5 ml for mature stock (over 4 weeks), preventing under-dosing or unnecessary waste.
Versatile Delivery Routes: Fully approved for both subcutaneous and intramuscular injection, allowing facility managers to utilize their preferred administration technique.
Temperature Acclimation: Clear instructions dictate bringing the emulsion to ambient room temperature prior to use, ensuring optimal viscosity for rapid syringe refilling.
Homogenization Requirement: Operators are guided to agitate the bottle thoroughly, guaranteeing that the antigen suspension remains perfectly uniform from the first bird to the last.
Strict Aseptic Protocols: Emphasizes the necessity of sterile instruments and same-day utilization of opened vials, mitigating any risk of secondary bacterial contamination during the workflow.
Supply chain logistics and inventory management are critical components of large-scale agricultural procurement. The packaging architecture of this vaccine is designed to offer maximum adaptability for diverse operational scales.
Multiple Vial Capacities: Available in 100 ml, 250 ml, and 500 ml bottles, allowing managers to select the exact volume needed for specific house sizes, minimizing open-bottle waste.
Optimized Carton Configurations: Shipped in highly durable cartons containing 20, 24, 40, or 100 bottles, perfectly accommodating both regional distribution hubs and massive centralized farm complexes.
Standardized Cold Chain: Requires a standard 2~8°C storage environment, seamlessly integrating into existing pharmaceutical refrigeration infrastructure without the need for ultra-low temperature freezers.
Extended Shelf Life: The robust 12-month expiration window provides procurement departments with the confidence to order in economical volumes without the immediate threat of product degradation.
Strict Non-Freezing Mandate: Clear labeling ensures handlers understand that freezing will break the delicate emulsion, safeguarding the physical integrity of the product during winter transport.
Consistent biological performance is inextricably linked to the rigorous standards of the manufacturing facility. This product is the result of uncompromising quality assurance protocols.
Premier Manufacturing Origin: Produced by Qingdao Vland Animal Health Group Co., Ltd., a globally recognized entity synonymous with advanced veterinary biologicals.
Veterinary Supervision Mandate: Strictly classified for use under professional veterinary guidance, ensuring that deployment aligns with comprehensive flock health management strategies.
Stringent Production Standards: Every batch is synthesized within state-of-the-art, certified cleanrooms, guaranteeing absolute sterility and the absence of cross-contamination.
Batch-to-Batch Consistency: Rigorous internal auditing and post-production testing ensure that every vial delivers the exact same antigen titer and physical emulsion quality.
Reliable Procurement Partner: The established manufacturing pedigree provides large-scale purchasers and international distributors with unwavering confidence in supply chain stability and product efficacy.
Selecting the right biological partner is a strategic decision that impacts the entire agricultural production chain. Our commitment extends far beyond the liquid in the vial.
Unwavering Supply Consistency: We possess the infrastructure to fulfill massive volume requirements precisely on schedule, ensuring your vaccination programs are never delayed by stock shortages.
Rigorous Quality Assurance: From raw viral seed stock to final packaging, our multi-tiered inspection process guarantees that only flawless, high-titer emulsions reach your facility.
Technical Compatibility: Our formulations are rigorously tested to ensure seamless integration with modern, automated mass-vaccination equipment utilized in contemporary farming.
Long-Term Economic Value: By dramatically reducing mortality and optimizing flock health, our biological solutions provide a measurable, high return on your preventative health investment.
Dedicated Professional Support: Backed by extensive veterinary expertise, we provide the documentation and guidance necessary to support complex, multi-site immunization strategies.
Freezing fundamentally alters the physical structure of the vaccine, which relies on a precise balance of liquids.
It causes the emulsion to break, irreversibly separating the aqueous and lipid phases.
The sustained-release mechanism of the adjuvant is entirely destroyed.
Administration of a broken emulsion can cause severe localized inflammatory reactions and will fail to provide the intended immunity.
Temperature directly impacts the physical properties and viscosity of the milky-white liquid.
Cold emulsion is highly viscous, making it difficult to draw smoothly into automated syringes.
Injecting cold liquid significantly increases physiological stress and temperature shock on the birds.
Allowing it to reach room temperature ensures smooth flow, precise dosing, and better absorption at the injection site.
Mixing biologicals without explicit manufacturer approval is highly discouraged and compromises efficacy.
The adjuvant in the inactivated emulsion can negatively interact with and neutralize live viral particles.
It may alter the absorption rate and immunological cascade of both products.
Always administer separate vaccines at different injection sites unless they are specifically formulated and approved as a combination product.
The Clone 30 strain is specifically selected for its optimal balance of safety and high immunogenicity.
It is a highly purified, lentogenic-derived strain known for its stable genetic profile.
It elicits a profound humoral immune response without causing the severe respiratory distress associated with stronger strains.
It is universally recognized by veterinary professionals as a gold standard for commercial poultry protection against systemic NDV challenges.
Maintaining absolute sterility is paramount when handling veterinary biologicals to protect flock health.
Once the rubber septum is punctured, the sterile seal is compromised, exposing the emulsion to environmental contaminants.
Any remaining liquid must be safely discarded and disinfected at the end of the vaccination day.
Never store opened bottles overnight for use the following day, as bacterial growth within the emulsion can cause severe post-injection infections.
